At CD BioSciences, we offer a broad range of Bioanalytical & Biomarker Services to support research and preclinical studies in the field of human herpesvirus (HHV). Our services are tailored to meet the highest scientific and regulatory standards, assisting pharmaceutical companies, research institutions, and biotechnology firms in the development of novel antiviral therapies and vaccines. Our team of experts employs state-of-the-art techniques to ensure the accuracy and reliability of your data, providing valuable insights into the mechanisms of action, pharmacokinetics, and immunogenicity of your candidate products.
Method Development & Validation
We specialize in the development and validation of bioanalytical methods to ensure the precision and consistency of your results. Whether required for Good Laboratory Practice (GLP) or non-GLP studies, our team ensures that all methods are fully validated for use in antiviral research. We offer solutions for a variety of assays including quantitative and qualitative biomarker detection, ensuring reliable support throughout your development pipeline.
Pharmacokinetics & Toxicokinetics Analysis
Understanding the pharmacokinetics (PK) and toxicokinetics (TK) of drug candidates is crucial for assessing their therapeutic potential and safety profile. CD BioSciences provides comprehensive PK and TK analysis using advanced techniques such as LC-MS/MS. We analyze drug absorption, distribution, metabolism, and excretion (ADME) to optimize drug development and enhance clinical success rates.
Small Molecule Bioanalysis (LC-MS/MS)
Our laboratory is equipped with the latest LC-MS/MS technology for highly sensitive and specific small molecule bioanalysis. This service supports viral research, including the detection and quantification of small molecule antiviral agents in biological matrices. We provide reliable data for the analysis of pharmacokinetic profiles, therapeutic efficacy, and safety.
Large Molecule & Biologics Bioanalysis
We offer large molecule and biologics bioanalysis using techniques like Ligand Binding Assays (LBA) and Enzyme-Linked Immunosorbent Assay (ELISA). This service is essential for evaluating the immunogenicity of biologics, such as monoclonal antibodies and vaccines. Our assays enable the detection and quantification of biomarkers, including immune responses and antibodies, in complex biological matrices.
Viral Load & Biodistribution
Viral load and biodistribution analysis are critical in assessing the effectiveness of antiviral drugs and therapies targeting HHV. CD BioSciences uses advanced quantitative PCR (qPCR) and droplet digital PCR (ddPCR) techniques to precisely measure viral titers in biological samples. This service helps monitor viral replication, assess treatment efficacy, and ensure the safety of gene therapy products.
Viral Shedding Analysis
Viral shedding analysis is key to evaluating the potential risks and benefits of antiviral therapies. Using advanced molecular techniques, we provide accurate quantification of viral shedding in clinical and preclinical studies. This service is essential for understanding the potential transmission risks associated with viral infections and the impact of antiviral treatments on viral load.
Immunogenicity & Anti-Drug Antibody Assays
To evaluate the potential immune responses to biologics, we offer immunogenicity testing and Anti-Drug Antibody (ADA) assays. These assays are crucial for assessing whether a drug or vaccine triggers an immune response, which could impact its safety and efficacy. Our assays are designed to provide accurate and sensitive detection of antibodies, ensuring that your therapeutic product is well-characterized and safe for use.
Biomarker Discovery & Validation
Our Biomarker Discovery & Validation service provides a comprehensive approach to identifying and validating biomarkers that can predict treatment outcomes, disease progression, and patient response to therapy. By leveraging cutting-edge technologies and a deep understanding of virology, we help you discover novel biomarkers for the monitoring of HHV-related diseases and therapeutic interventions.
FAQs
Custom Reviews
Review 1:
"CD BioSciences provided excellent support in our antiviral drug development project. Their bioanalytical services, especially in pharmacokinetics and viral load analysis, have been crucial for advancing our therapeutic candidate."
Review 2:
"The team at CD BioSciences has been instrumental in helping us validate biomarkers for our HHV vaccine. Their expertise in biomarker discovery and immunogenicity testing ensured that our development was on the right track."